Endocrine Abstracts

Silent corticoptroph adenomas (SCA) are pituitary tumours positive on immunohistochemical staining for ACTH but without clinical evidence of hypercortisolism. They account for 1.1–6% of surgically removed pituitary adenomas. Most tumours are macroadenomas with suprasellar extension present in 87–100% of the cases. They present with mass effects and this is in contrast to Cushing’s disease, which is mostly attributed to microadenomas. Reports suggest that these t...

Background: Primary or idiopathic empty sella syndrome (ESS) is the herniation of the meninges through an incompetent diaphragma sellae into the sella turcica which pushes the pituitary gland aside so giving the appearance of an empty sella. Secondary ESS is caused by damage to pituitary tissue which results in an empty sella turcica. There is significant lack of agreement in the literature regarding the number of patients with empty sella syndrome (ESS) who suffer from pituit...